RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules. RNAi controls can be used to accurately interpret the results of experiments involving the RNAi pathway.
The siRNA (annealed) is shipped at ambient temperature as dried down oligonucleotides in a single tube, along with 1.75 ml Nuclease-free Water for resuspension. Store at or below –20°C.
Ambion™ In Vivo siRNAs are designed using the proven Silencer™ Select algorithm and incorporate chemical modifications for superior serum stability with in vivo delivery.
miRNA mimics are small, chemically modified double-stranded RNA molecules designed to specifically bind to and mimic endogenous miRNA molecules and enable miRNA functional analysis by up-regulation of miRNA activity.
Silencer Negative Control No. 1 siRNA is a bioinformatically designed, non-targeting siRNA crucial for siRNA experiments. Matching Silencer chemistry, it is an essential negative control siRNA for achieving clear, accurate gene silencing results.
mirVana miRNA Mimic Negative Control No. 1 is a non-targeting control for experiments with mirVana miRNA mimics. Providing a baseline for evaluating miRNA gene expression effects, this miRNA mimic negative control is validated to ensure no impact on known miRNA functions in human cells.
mirVana miRNA Inhibitor Negative Control No. 1 is a non-targeting control for miRNA inhibition experiments. It provides a baseline for evaluating effects on gene expression. Extensively tested in human cells, it ensures no impact on known miRNA functions.