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Gibco™ Mouse IL-10 ELISA Development Kit (TMB), PeproTech®

Numéro de catalogue. 900T53K
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10 x 96 Tests
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Numéro de catalogue. Quantité
900T53K 10 x 96 Tests
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Numéro de catalogue. 900T53K Fournisseur Gibco™ Code fournisseur 900T53K

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Description

ELISA

900-T53K consists of: 900-T53 (capture antibody, detection antibody, and protein standard), and HRP-17UL (streptavidin HRP-conjugate). Mouse IL-10 TMB ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinantmouse IL-10 in a sandwich ELISA format. Mouse IL-10 TMB ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells. The TMB ELISA Buffer Kit (Product # 900-T00), sold separately, is recommended to be used in conjunction with this TMB ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

Spécifications

Numéro d'enregistrement P18893
Plage de l'essai Lot-specific
Sensibilité d’essai Lot-specific
Conjugué HRP
Format de la trousse d’immunodosage Sandwich ELISA Kit
Type de produit ELISA
Famille de protéines Growth Factors & Receptors
Espèces cibles Mouse
À utiliser avec (équipement) Absorbance Microplate Reader
Alias du gène CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIFCSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF;
ID du gène (Entrez) 16153
Symbole de gène IL10
Contenus des kits This Mouse IL-10 ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately., Detection Antibody, Protein Standard, HRP-conjugate
Étiquette ou colorant Biotin
Quantité 10 x 96 Tests
Statut réglementaire RUO
Shipping condition (Condition d'expédition) Room temperature
Conditions de stockage Refer to product documentation for component specific storage temperature.
Cible IL-10
Durée du test 1 hr 45 min
Durée totale de l'essai 24 hr 30 min
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