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Invitrogen™ Rat DKK-1 ELISA Kit

ELISA

$938.00 - $4,420.00

Spécifications

Accession Number dickkopf 1 homolog; dickkopf homolog 1; dickkopf homolog 1 (Xenopus laevis); dickkopf related protein-1; dickkopf WNT signaling pathway inhibitor 1; Dickkopf1; dickkopf-1; dickkopf-1 like; dickkopf-like protein 1; dickkopf-related protein 1; DKK1; DKK-1; hDkk1; hDkk-1; mdkk-1; SK; UNQ492/PRO1008
Assay Range 33 to 8,000 pg/mL
Assay Sensitivity 33 pg/mL
Conjugate HRP
Product Type ELISA
voir les spécifications

Produits 2
Numéro de catalogue Numéro du manufacturier. Quantity Prix Quantity & Availability  
Numéro de catalogue Numéro du manufacturier. Quantity Prix Quantity & Availability  
ERA9RBX5
Encompass
Afficher les documents Détails de la promotion
Invitrogen™
ERA9RBX5
5 x 96 Tests
chaque for $4,420.00
Il en reste null
 
ERA9RB
Encompass
Afficher les documents Détails de la promotion
Invitrogen™
ERA9RB
96 Tests
chaque for $938.00
Il en reste null
 
Description

Description

Rat DKK-1 quantitates rat DKK-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat DKK-1.

DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head-forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play important regulatory roles in the Wnt/beta-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/beta-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/beta-catenin signaling cascade. It has been suggested that by inhibiting Wnt/beta-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis.
Spécifications

Spécifications

dickkopf 1 homolog; dickkopf homolog 1; dickkopf homolog 1 (Xenopus laevis); dickkopf related protein-1; dickkopf WNT signaling pathway inhibitor 1; Dickkopf1; dickkopf-1; dickkopf-1 like; dickkopf-like protein 1; dickkopf-related protein 1; DKK1; DKK-1; hDkk1; hDkk-1; mdkk-1; SK; UNQ492/PRO1008
33 pg/mL
ELISA
Colorimetric Microplate Reader
DKK1
<10
HRP
Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
DKK1
4 hrs 45 mins
33 to 8,000 pg/mL
HRP
Plasma, Serum, Supernatant
293897
<12%
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
RUO
2°C to 8°C
1 hrs 20 mins
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