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Alfa Aesar™ Leupeptin hemisulfate

Reversible protease inhibitor which inhibits cathepsin B, calpain and trypsin

$205.11 - $507.35

Chemical Identifiers

CAS 103476-89-7
Molecular Formula C20H39N6O4+
Molecular Weight (g/mol) 427.57
MDL Number MFCD00037012
InChI Key GDBQQVLCIARPGH-ULQDDVLXSA-O
Synonym leupeptin, leupeptin hemisulfate, leupeptin hemisulfate from microbial*source, acetyl-leu-leu-arg-al, leupeptin hemisulfate salt, n-acetyl-l-leucyl-l-leucyl-l-argininal hemisulfate salt, diaminomethylidene 4s-4-2s-2-2s-2-acetamido-4-methylpentanamido-4-methylpentanamido-5-oxopentyl azanium, 4s-4-2s-2-2s-2-acetamido-4-methylpentanoyl amino-4-methylpentanoyl amino-5-oxopentyl-diaminomethylidene azanium, amino 4s-4-2s-2-2s-2-acetamido-4-methylpentanamido-4-methylpentanamido-5-oxopentyl amino methylidene azanium
PubChem CID 7098622
IUPAC Name [(4S)-4-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-oxopentyl]-(diaminomethylidene)azanium
SMILES CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCC[NH+]=C(N)N)C=O)NC(=O)C
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ61188MB View Documents Alfa Aesar™
J61188MB
25mg Each for $205.11
 
AAJ61188MC View Documents Alfa Aesar™
J61188MC
100mg Each for $507.35
 
Description

Description

Applications
Reversible protease inhibitor, which inhibits cathepsin B, calpain and trypsinPharmaceutical composition containing leupeptin hemisulfate is used as an anti-malarial agent. It is employed in the treatment of noise-induced hearing loss. It also protects the heart from myocardial stunning. Further, it is used to inhibit serine, cysteine proteases, plasmin, trypsin, papain, kallikrein and cathepsin B.

Solubility
Soluble in water, ethanol, dimethyl formamide and acetic acid.

Notes
Store in a cool place. Incompatible with strong acids and strong bases.
Specifications

Chemical Identifiers

103476-89-7
427.57
GDBQQVLCIARPGH-ULQDDVLXSA-O
7098622
CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCC[NH+]=C(N)N)C=O)NC(=O)C
C20H39N6O4+
MFCD00037012
leupeptin, leupeptin hemisulfate, leupeptin hemisulfate from microbial*source, acetyl-leu-leu-arg-al, leupeptin hemisulfate salt, n-acetyl-l-leucyl-l-leucyl-l-argininal hemisulfate salt, diaminomethylidene 4s-4-2s-2-2s-2-acetamido-4-methylpentanamido-4-methylpentanamido-5-oxopentyl azanium, 4s-4-2s-2-2s-2-acetamido-4-methylpentanoyl amino-4-methylpentanoyl amino-5-oxopentyl-diaminomethylidene azanium, amino 4s-4-2s-2-2s-2-acetamido-4-methylpentanamido-4-methylpentanamido-5-oxopentyl amino methylidene azanium
[(4S)-4-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-oxopentyl]-(diaminomethylidene)azanium

Specifications

White
103476-89-7
MFCD00037012
Soluble in water at 50mg/ml
CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCC[NH+]=C(N)N)C=O)NC(=O)C
427.57
475.59
Leupeptin hemisulfate
25mg
C20H39N6O4+
leupeptin, leupeptin hemisulfate, leupeptin hemisulfate from microbial*source, acetyl-leu-leu-arg-al, leupeptin hemisulfate salt, n-acetyl-l-leucyl-l-leucyl-l-argininal hemisulfate salt, diaminomethylidene 4s-4-2s-2-2s-2-acetamido-4-methylpentanamido-4-methylpentanamido-5-oxopentyl azanium, 4s-4-2s-2-2s-2-acetamido-4-methylpentanoyl amino-4-methylpentanoyl amino-5-oxopentyl-diaminomethylidene azanium, amino 4s-4-2s-2-2s-2-acetamido-4-methylpentanamido-4-methylpentanamido-5-oxopentyl amino methylidene azanium
GDBQQVLCIARPGH-ULQDDVLXSA-O
[(4S)-4-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-oxopentyl]-(diaminomethylidene)azanium
7098622
Powder
Safety and Handling

Safety and Handling

Recommended Storage : −30° to −10°C