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Specifications
| Accession Number | 3.4.24.65; AV378681; HME; Macrophage elastase; Macrophage metalloelastase; macrophage-metalloelastase; matrix metallo protease; matrix metallopeptidase 12; matrix metallopeptidase 12 (macrophage elastase); matrix metalloproteinase 12; matrix metalloproteinase 12 (macrophage elastase); matrix metalloproteinase-12; ME; MGC138506; Mme; Mmel; MMP; MMP12; MMP-12; MMPs |
|---|---|
| Assay Range | 0.04 to 10 ng/mL |
| Assay Sensitivity | 0.04 ng/mL |
| Conjugate | HRP |
| Product Type | ELISA |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
EH327RBX5
|
Invitrogen™
EH327RBX5 |
5 x 96 Tests |
Each for $4,330.00
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EH327RB
|
Invitrogen™
EH327RB |
96 Tests |
Each for $858.00
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Description
Human MMP-12 quantitates human MMP-12 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human MMP-12.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.Specifications
| 3.4.24.65; AV378681; HME; Macrophage elastase; Macrophage metalloelastase; macrophage-metalloelastase; matrix metallo protease; matrix metallopeptidase 12; matrix metallopeptidase 12 (macrophage elastase); matrix metalloproteinase 12; matrix metalloproteinase 12 (macrophage elastase); matrix metalloproteinase-12; ME; MGC138506; Mme; Mmel; MMP; MMP12; MMP-12; MMPs | |
| 0.04 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| Mmp12 | |
| <10 | |
| HRP | |
| Plasma 50 μL, Serum 50 μL, Supernatant 50 μL | |
| MMP12 | |
| 4 hrs 45 mins |
| 0.04 to 10 ng/mL | |
| HRP | |
| Plasma, Serum, Supernatant | |
| 4321 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| RUO | |
| 2°C to 8°C | |
| 1 hrs 20 mins |