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Invitrogen™ Human Factor VII Native Protein

Catalog No. PIRP43068
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20 μg
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Catalog No. Quantity
PIRP43068 20 μg
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Catalog No. PIRP43068 Supplier Invitrogen™ Supplier No. RP43068
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Description

Native Protein

RP-43068 contains native human Factor VII protein. RP-43068 may be used as a positive control in many immunological assays. The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.

Specifications

Accession Number P08709
Concentration 1.4 mg/mL
For Use With (Application) Control
Formulation 50% water with 50% glycerol and no preservative
Gene ID (Entrez) 2155
Molecular Weight (g/mol) 50 kDa
Name Human Factor VII
Quantity 20 μg
Source Human
Regulatory Status RUO
Gene Alias AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA
Common Name Factor VII
Gene Symbol F7
Conjugate Unconjugated
Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Form Liquid
Protein Subtype Native
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