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  6. Thermo Scientific Chemicals Cyclosporin A, 98%

Thermo Scientific Chemicals Cyclosporin A, 98%

Catalog No. AC457970010
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Catalog No. AC457970010 Supplier Thermo Scientific Chemicals Supplier No. 457970010
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Description

Cyclosporin A, 98%, CAS # 59865-13-3, is a compound that shows immunosuppressive, antifungal, antirheumatic, and dermatologic activities. It is also a calcineurin and enzyme inhibitor. | CAS: 59865-13-3 | C62H111N11O12 | 1202.64 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Cyclosporin A is a non-polar cyclic oligopeptide produced by the fungus Tolypocladium inflatum

Chemical Identifiers

CAS 59865-13-3
Molecular Formula C62H111N11O12
Molecular Weight (g/mol) 1202.64
MDL Number MFCD00274558
InChI Key PMATZTZNYRCHOR-IMVLJIQENA-N
PubChem CID 132274082
SMILES CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C

Specifications

Type Cyclosporin A
Melting Point 146.0°C to 151.0°C
Infrared Spectrum Authentic
Loss on Drying 2% max. (60°C, 3 hrs, 5 mm Hg)
Quantity 1 g
IUPAC Name 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
Formula Weight 1202.61
Percent Purity 98%
Chemical Name or Material Cyclosporin A

Safety and Handling

Hazard Category Danger
Hazard Statement GHS H Statement Harmful if swallowed. May cause cancer. May damage fertility. May damage the unborn child.
Precautionary Statement GHS P Statement Wash face, hands and any exposed skin thoroughly after handling. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Obtain special instructions before use. Use personal protective equipment as required. IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only