missing translation for 'onlineSavingsMsg'
Learn More
Learn More
MilliporeSigma™ Calbiochem™ Cyclopamine, V. californicum
Cyclopamine, V. californicum, CAS 4449-51-8, is a cell-permeable steroidal alkaloid & cholesterol mimic that specifically antagonizes Sonic Hedgehog signaling through direct interaction with Smo.
$306.21 - $306.21
Specifications
| Color | Off-white |
|---|---|
| Target Proteins | Hh signaling in Shh-light2 assay |
| CAS | 4449-51-8 |
| Molecular Formula | C27H41NO2 |
| Formula Weight | 411.6g/mol |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|
23-980-31MG
|
MilliporeSigma™
2398031MG |
1 mg |
Each for $306.21
|
|
|||||
Description
A cell-permeable steroidal alkaloid and cholesterol mimic that displays both teratogenic and antitumor activities. It disrupts cholesterol bio-synthesis and specifically antagonizes shh (Sonic Hedgehog) signaling pathway through direct interaction with Smo (smoothened), a distant relative of G-protein-coupled receptors. A valuable tool for studying the involvement of shh signaling in the development of various tumors. Tomatidine (Cat. No. 614350) can be used as a negative control. Also available as a 10mm solution in Ethanol (Cat. No. 239806).Specifications
| Off-white | |
| 4449-51-8 | |
| 411.6g/mol | |
| Protect from light | |
| 97% by HPLC |
| Hh signaling in Shh-light2 assay | |
| C27H41NO2 | |
| DMSO, EtOH, or DMF | |
| Solid |