Inert physical filtration devices, typically installed before pre-columns, that provide a coarse filtration of the HPLC eluent and prevent contaminant particles from reaching the HPLC system.
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Frits are crucial components of the high performance liquid chromatography system design. They act as a depth filter for the concurrent physical removal of small molecules. Medium, 20 μm porosity frits are used for crystalline precipitates and extraction applications.
Described in US EPA Protocol - Fill columns with appropriate adsorbents when cleaning or drying environmental samples for pesticide or priority pollutant analyses