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Cryostats and Accessories

Instruments used to cut histology slides and/or maintain low temperatures of samples or devices mounted within them. Products also include cryostat accessories and replacement parts such as specimen chucks, freezing sprays, and blade carriers.

Cryostats are typically located in the surgical area of a healthcare facility to allow for immediate examination of tissue pathology, usually during surgical procedures. The examination of tissue during a surgical procedure helps the surgeon determine whether additional tissue should be removed or further surgery is required.

Cryostats operate like microtomes for tissue sectioning, but the tissue is not processed chemically to prepare it for sectioning. Instead, freezing makes the tissue solid enough to be sliced. Excess tissue from the frozen section sample is then sent to the histology laboratory for chemical tissue processing, sectioning, staining, and more extensive evaluation by a pathologist.

The excised tissue is embedded in frozen section media for faster freezing and to create a bond between the tissue and the specimen stage or specimen chuck that holds it. The media also helps reduce tissue curling and artifacts from ice formation.

Cryostats may be electrical or, less commonly, use liquid nitrogen or helium to rapidly freeze the tissue specimens. Although more frequently used in healthcare, cryostats may also be used in research settings.

Current models may also feature:

  • Automatic UV disinfection
  • Motorized handwheel
  • Peltier temperature controls
  • Multiple freezing stations
  • Touchscreen operation
  • Ergonomic design
  • Emergency stop via foot pedal or control panel
  • Debris removal systems

Additional cryostat accessories and replacement cryostat parts and blades are also available

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1 – 15 of 35 results
1

Epredia™ CryoStar™ NX50 Cryostat

Manual cryostat designed to accommodate the needs of the routine clinical laboratory by offering a form-fitting ergonomic design, with optional height adjustment, vacutome and cold D disinfection.

Height (Metric) 82 to 112 cm
Depth (English) 39.4 in.
Width (English) 29.7 in.
Cutting Window Manually adjusted to specimen size
Width (Metric) 75.5 cm
Sectioning Range 0.5 to 100μm (Fine Section), 5 to 500μm (Trim Section)
Horizontal Specimen Movement 48 mm
Clearance Angle Adjustment Disposable blade carrier 8 to 16°
Specimen Retraction 20 μm
Trim Section Resolution 5 to 30μm in 5μm steps; 30 to 100μm in 10μm steps; 100 to 200μm in 20μm steps; 200 to 500μm in 50μm steps
Product Type Cryostat
Depth (Metric) 100 cm
Defrost Programmed/Immediate
Cryobar Cooling -57°C ±3°C (-70.6°F +35.6° to -26.6°F) at +20°C/+58°F ambient
Fine Section Resolution 0.5 to 5μm in 0.5μm steps; 5 to 10μm in 1μm steps; 10 to 20μm in 2μm steps; 20 to 50μm in 5μm steps; 50 to 100μm in 10μm steps
Specimen Orientation y-axes 8° adjustable for increased stability; Z axis adjustable 360°
Weight (English) 440 lb.
Cutting Drive Manual
Vertical Cutting Stroke 64 mm
Specimen Temperature Control 43 ±2°C at +20°C Room Temperature
Blade Holder Approach Stepper motor controlled through simple touch screen display
Coarse Feed Motorized (on/off)
Weight (Metric) 200 kg
Height (English) 32.3 to 44.0 in.
Knife Temperature Control -27°C to -20°C ±2°C at +20° to +30°C Room Temperature
2

Epredia™ HM525 NX Cryostat

A high performance routine cryostat with intuitive software and touchscreen for simple, efficient operation

Electrical Requirements 115 V 60 Hz
3

Epredia™ CryoStar™ NX50 Cryostat With Blade Carrier

Manual cryostat designed to accommodate the needs of the routine clinical laboratory by offering a form-fitting ergonomic design, with optional height adjustment, vacutome and cold D disinfection.

Product Type Cryostat with Carrier
4

Epredia™ CryoStar™ NX70 Cryostat

Accommodate the needs of both research and clinical laboratories with the Epredia™ CryoStar™ NX70.

Width (English) 29.7 in.
Chamber Temperature -60°C Max.
Cutting Window Manually adjusted to specimen size
Width (Metric) 75.5 cm
Includes All standard features: electronic height adjustment, Rapid Response Temperature Control, multi-axis specimen orientation, motorized sectioning, specimen retraction, form-fitting design
Lighting LED
Defrost Programmed/Immediate
Fine Section Resolution 0.5 to 5μm in 0.5μm steps; 5 to 10μm in 1μm steps; 10 to 20μm in 2μm steps; 20 to 50μm in 5μm steps; 50 to 100μm in 10μm steps
Specimen Orientation x- and y-axes universal 7° with zero positioning; z-axis up to 360°
Certifications/Compliance Certificate of Hygiene, CE Marked
Vertical Cutting Stroke 64 mm
Weight (Metric) 200 kg
Height (English) 32.3 to 44.0 in.
Height (Metric) 82 to 112 cm
Specimen Approach Manual 3 mm/sec. max. (variable speed by joystick control)
Depth (English) 39.4 in.
Cutting Speed 0 to 256 mm/sec.
Sectioning Range 0.5 to 100μm (Fine Section), 5 to 500μm (Trim Section)
Horizontal Specimen Movement 48 mm
Clearance Angle Adjustment Disposable blade carrier 8 to 16°
Specimen Retraction 20 μm
Trim Section Resolution 0.5 to 5μm in 0.5μm steps, 5 to 10μm in 1μm steps, 10 to 20μm in 2μm steps, 20 to 50μm in 5μm steps, 50 to 100μm in 10μm steps
Depth (Metric) 100 cm
Weight (English) 440 lb.
Cutting Drive Manual and motorized, electronically controlled
Specimen Temperature Control -50°C to +10°C at +20°C Room Temperature (decrease 0.7°C/1°C room temp. increase)
Coarse Feed Motorized (on/off)
Knife Temperature Control -35°C to -5°C at 20°C room temp. (decrease 0.5°C/1°C room temp. increase)
Display Integrated Color LCD Touchscreen
5

Mopec™ Specimen Chucks for Leica CM1950 Cryostat, 30 mm

Specimen Chucks are available in multiple sizes and colors. Some chucks are also available in waffle pattern.

For Use With (Equipment) Leica CM1950 Cryostat
6

Epredia™ CryoStar™ NX70 Specimen Chucks

Choose between multiple available colors for Epredia™; CryoStar™ Cryostat Specimen Chucks.

7

Mopec™ Specimen Chucks for CRYOSTAR Cryostats, 40 mm

Specimen Chucks are available in multiple sizes and colors. Some chucks are also available in waffle pattern.

For Use With (Equipment) CryoStar NX50 and NX70
Material Aluminum
9

Epredia™ CryoStar™ NX50 and NX70 Accessories

Enhance operation of Epredia™ CryoStar™ NX50 and NX70 Cryostats with Epredia™ CryoStar™ NX50 and NX70 Accessories.

10

Epredia™ Specimen Stages for HM 520, 525, 550 and 560

Use Epredia™ Specimen Stages for Epredia HM 520, 525, 550 and 560 Series Cryostats.

Product Type Specimen Stage
11

Mopec™ Specimen Chucks for CRYOSTAR Cryostats, 30 mm

Specimen Chucks are available in multiple sizes and colors. Some chucks are also available in waffle pattern.

For Use With (Equipment) CryoStar NX50 and NX70
12

Mopec™ Circular Specimen Chucks for Leica, TBS, and Tanner Cryostats

Available in multiple sizes and colors for use with Leica, TBS, and Tanner Cryostats.

For Use With (Equipment) Leica, TBS, and Tanner Cryostats
13

Mopec™ Waffle Specimen Chucks for SHANDON Cryostats

Waffle Specimen Chucks are available in multiple sizes and colors.

For Use With (Equipment) SHANDON Cryostats
Product Type Waffle Chuck
14

Epredia™ HM 525 NX Cryostat Blade Holders

Use Epredia™ HM 525 NX blade holders with HM 525 NX and other Epredia™ cryostats.

15

Epredia™ Disposable Blade Carriers

Utilize a quick clamp system that accepts low- and high-profile blades