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Tocris Bioscience™ VU 0357017 hydrochloride
Description
Positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM). Displays no activity at M2-M5 at concentrations up to 30 μM. Potentiates NMDA receptor currents in hippocampal neurons; activity reverses cognitive decifits in a rodent model of hippocampal-dependent memory. CNS penetrant.
Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 369.89 |
| Purity | >98% |
| Molecular Weight (g/mol) | 369.89 |
| Chemical Name or Material | VU 0357017 hydrochloride |
Safety and Handling
| Recommended Storage | Store at +4°C |