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Invitrogen™ TTR Monoclonal Antibody (2E10C5)
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Numéro de catalogue. PIMA1221
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Quantité:
100 μg
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Numéro de catalogue. Quantité
PIMA1221 100 μg
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Numéro de catalogue. PIMA1221 Fournisseur Invitrogen™ Code fournisseur MA1221

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Description

Mouse Monoclonal Antibody

MA1-221 detects Transthyretin protein in ELISA and Western Blot applications. The MA1-221 immunogen is the purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli.

Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.

Spécifications

Antigène TTR
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2E10C5
Concentration 1 mg/mL
Conjugué Unconjugated
Formule PBS with 0.05% sodium azide
Gène TTR
Numéro d’acquisition du gène P02766
Alias du gène AA408768; AI787086; Amyloidosis I; ATTR; carpal tunnel syndrome 1; CTS; CTS1; D17860; epididymis luminal protein 111; HEL111; HsT2651; Lr1; PALB; prealbumin; pre-albumin; prealbumin, amyloidosis type I; Tbpa; thyroxine-binding prealbumin; transthyretin; Tt; TTR
Symboles de gène TTR
Espèces hôtes Mouse
Immunogène Purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli.
Méthode de purification Protein A
Quantité 100 μg
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 7276
Espèces cibles Human
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG1
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