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Invitrogen™ TGFBR1 Monoclonal Antibody (234R32)
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Numéro de catalogue. AHO1552
Encompass
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Quantité:
100 μg
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Numéro de catalogue. Quantité
AHO1552 100 μg
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Numéro de catalogue. AHO1552 Fournisseur Invitrogen™ Code fournisseur AHO1552

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Description

Mouse Monoclonal Antibody

TGFBR1 Monoclonal Antibody for Western Blot

TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1. TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).

Spécifications

Antigène TGFBR1
Applications Western Blot
Classification Monoclonal
Clone 234R32
Concentration 0.5 mg/mL
Conjugué Unconjugated
Formule PBS with 0.1% sodium azide; pH 7.4
Gène TGFBR1
Numéro d’acquisition du gène P36897, P80204
Alias du gène AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I
Symboles de gène TGFBR1
Espèces hôtes Mouse
Immunogène Recombinant human TGF-b R1 extracellular fragment.
Méthode de purification Affinity chromatography
Quantité 100 μg
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 29591, 7046
Espèces cibles Human, Rat
Contenu et stockage -20°C
Type de produit Antibody
Forme Liquid
Isotype IgG1 κ
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