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Tacrine hydrochloride

Numéro de catalogue. AAJ6007006
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AAJ6007006 5 g
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Numéro de catalogue. AAJ6007006 Fournisseur Thermo Scientific Chemicals Code fournisseur J6007006
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Description

A potent centrally acting anticholinesterase | CAS: 1684-40-8 | C13H15ClN2 | 234.73 g/mol

A potent centrally acting anticholinesterase for therapy of memory deficits in patients with Alzheimer's disease. THA also selectively blocks potassium channels in the central nervous system, which results in an increased release of acetylcholine and a prolongation of the action potential of the presynaptic cholinergic neurons.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in aqueous buffers

Notes
Refrigerate. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Spécifications

CAS 1684-40-8
Melting Point 283°C to 284°C
Color Yellow
Molecular Formula C13H15ClN2
Quantity 5 g
MDL Number MFCD00150067
UN Number UN2811
Merck Index 14,9024
Synonym tacrine hydrochloride, 1,2,3,4-tetrahydroacridin-9-amine hydrochloride, tacrine hcl, hydroaminacrine, tenakrin, 9-amino-1,2,3,4-tetrahydroacridine hydrochloride, tacrine.hcl, unii-4966rng0bu, 1,2,3,4-tetrahydro-9-acridinamine hydrochloride, ccris 7250
Solubility Information Soluble in aqueous buffers
InChI Key ZUFVXZVXEJHHBN-UHFFFAOYSA-N
SMILES [H+].[Cl-].NC1=C2C=CC=CC2=NC2=C1CCCC2
IUPAC Name hydrogen 1,2,3,4-tetrahydroacridin-9-amine chloride
Molecular Weight (g/mol) 234.73
PubChem CID 2723754
Formula Weight 234.73 (Anhydrous)
Percent Purity ≥98%
Physical Form Crystalline Solid
Chemical Name or Material Tacrine hydrochloride
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Sécurité et manipulation

Hazard Category H302+H332-H315-H319-H335
Hazard Statement GHS H Statement
H331-H302-H315-H319-H335
Toxic if inhaled.
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber 216-867-5
RTECSNumber AR9532500
TSCA No
Recommended Storage Keep cold

RUO – Research Use Only