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Invitrogen™ SSEA4 Monoclonal Antibody (MC-813-70), DyLight™ 488

Description
MA1-021-D488 has been successfully used in ICC/IF and flow cytometry applications on human samples.
SSEA-4 (Stage-specific embryonic antigen 4) is a cell surface antigen, expressed along with SSEA-3, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA-1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.
Spécifications
Spécifications
| Antigène | SSEA4 |
| Applications | Flow Cytometry, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | MC-813-70 |
| Concentration | 1 mg/mL |
| Conjugué | DyLight 488 |
| Formule | PBS with proprietary stabilizer and 0.02% sodium azide |
| Alias du gène | SSEA-4; stage-specific embryonic antigen 4 |
| Espèces hôtes | Mouse |
| Immunogène | human embryonal carcinoma cell line 2102Ep. |
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