Corning™ Spin-X™ UF Concentrators

Description

Providing that the appropriate device size and membrane cut-off is selected, Corning Spin-X UF products will typically yield recoveries of the concentrated sample in excess of 90% when the starting sample contains over 0.1mg/mL of the solute of interest. Depending on sample characteristics relative to the membrane type used, solute adsorption
on the membrane surface is typically 2 to 10 ++g/cm2. This can increase to 20 to 100 ++g/cm2
when the filtrate is of interest and the solute must pass through the whole internal structure
of the membrane.

• General purpose polyethersulfone membranes for excellent retentate recovery
• Llow fouling, exceptional flux and broad pH range Polyethersulfone membranes exhibit no hydrophobic or hydrophilic interactions
• Advanced designs and low adsorption materials offer faster processing speeds and higher recovery of the concentrated samples

Corning offers Spin-X™ UF concentrators in three sizes.
Spin-X™ UF 500 for 100 to 500μL samples

• Made of Polycarbonate body and concentrator cap; Polypropylene Filtrate vessel
• One step procedure for sample preparation
• Effectively be used in fixed angle rotors accepting 2.2mL centrifuge tubes
• Patented vertical membrane design and thin channel filtration chamber minimizes membrane fouling and provides high speed concentrations, even with particle laden solutions

Spin-X™ UF 6 for 2 to 6mL samples

• Made of Polycarbonate body and Filtrate vessel; Polypropylene concentrator cap
• Offer increased volume flexibility and performance
• Process up to 6mL in swing bucket or fixed angle rotors accepting standard 15mL conical bottom tubes
• In a single spin, solutions can be concentrated in excess of 100-fold
• Samples are typically concentrated in 10 to 30 minutes with macromolecular recoveries in excess of 95%
• Features twin vertical membranes for unparalleled filtration speeds and 100x plus concentrations
• Remaining volume is easy to read off the printed scale on the side of the concentrator and the modified dead stop pocket further simplifies direct pipet recovery of the final concentrate

Spin-X™ UF 20 for 5 to 20mL samples

• Made of Polycarbonate body and Filtrate vessel; Polypropylene concentrator cap
• Offer increased volume flexibility and performance
• Handles up to 20mL in swing bucket centrifuges and 14mL in 25° fixed angle rotors accepting 50mL centrifuge tubes
• Featuring twin vertical membranes for unparalleled filtration speeds and achieve 100x plus concentrations
• Remaining volume is easy to read off the printed scale on the side of the concentrator and the modified dead stop pocket further simplifies direct pipet recovery of the final concentrate

General purpose laboratory concentration and desalting of proteins, enzymes, cells, biomolecules, antibodies and immunoglobulins
Removal of labeled amino acids and nucleotides
HPLC sample preparation
Deproteinization of samples
Recovery of biomolecules from cell culture supernatants, lysates

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