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Invitrogen™ Septin 2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA527517
Description
Recommended positive controls: U87-MG, SK-N-SH. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (94%), Xenopus laevis (94%), Pig (98%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements.Identifiants chimiques
| Septin 2 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human | |
| SEPTIN2 | |
| 2-Sep; AW208991; DIFF6; hNedd5; KIAA0158; mKIAA0158; NEDD5; Nedd-5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed, developmentally down-regulated gene 5; Pnutl3; Sept2; septin 2; Septin2; septin-2; Vascular endothelial cell specific protein 11; Vesp11 | |
| SEPTIN2 | |
| Primary | |
| Antigen affinity chromatography |
| 1 mg/mL | |
| Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q15019 | |
| 4735 | |
| Recombinant protein encompassing a sequence within the center region of human Septin 2. The exact sequence is proprietary. | |
| Antibody |
Spécifications
| Septin 2 | |
| Polyclonal | |
| Unconjugated | |
| SEPTIN2 | |
| 2-Sep; AW208991; DIFF6; hNedd5; KIAA0158; mKIAA0158; NEDD5; Nedd-5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed, developmentally down-regulated gene 5; Pnutl3; Sept2; septin 2; Septin2; septin-2; Vascular endothelial cell specific protein 11; Vesp11 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 4735 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q15019 | |
| SEPTIN2 | |
| Recombinant protein encompassing a sequence within the center region of human Septin 2. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |