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Invitrogen™ SEC23IP Polyclonal Antibody

Description
Immunogen sequence: HLELKESLSR MGSDLKQGFI SSLKSAWQTL NEFARAHTSS TQLQEELEKV ANQIKEEEEK QVVEAEKVVE SPDFSKDEDY LGKVGML Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 98%.
SEC23IP is involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway.
Spécifications
Spécifications
| Antigen | SEC23IP |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.10 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | SEC23IP |
| Gene Accession No. | Q6NZC7, Q9Y6Y8 |
| Gene Alias | D7Ertd373e; MSTP053; P125; P125A; SEC23 interacting protein; SEC23-interacting protein; Sec23-interacting protein p125; SEC23-interacting protein-like protein; SEC23IP |
| Gene Symbols | SEC23IP |
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