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Tocris Bioscience™ SB 4

Catalog No. 688150
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50 mg
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Catalog No. Quantity
688150 50 mg
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Catalog No. 688150 Supplier Tocris Bioscience™ Supplier No. 6881/50
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Description

Potent BMP4 agonist

SB 4 is a potent BMP4 agonist (EC50 = 74 nM). Activates canonical BMP signaling and increases SMAD-1/5/9 phosphorylation, with no effect on p-SMAD-2, p-SMAD-3 or p-TAK1. Bypasses noggin-induced inhibition of type I BMP receptors.

Specifications

Chemical Name or Material 2-[[(4-Bromophenyl)methyl]thio]benzoxazole
CAS 100874-08-6
Quantity 50 mg
Molecular Formula C14H10BrNOS
Formula Weight 320.2
Product Type Agonist
Purity 99%