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Tocris Bioscience™ SAHA

Catalog No. 465250
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50 mg
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Catalog No. Quantity
465250 50 mg
465210 10 mg
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Catalog No. 465250 Supplier Tocris Bioscience™ Supplier No. 4652/50
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Description

Class I and II HDAC inhibitor

SAHA inhibits Class I and II histone deacetylases (HDACs); induces accumulation of acetylated histones H2A, H2B, H3 and H4 in transformed cultured cells. Suppresses cell growth in a range of cancer cell lines; induces apoptosis in cutaneous T cell lymphoma cells in vitro. Activates autophagy. SAHA increases efficiency of transcription factor-induced reprogramming of mouse embryonic fibroblasts (MEF) to induced pluripotent stem cells (iPSC). Also enhances adeno-associated virus transduction of HeLa cells.

Chemical Identifiers

CAS 149647-78-9
Molecular Formula C14H20N2O3

Specifications

Quantity 50 mg
Formula Weight 264.32
Purity >98%
Molecular Weight (g/mol) 264.325
Chemical Name or Material SAHA

Safety and Handling

Recommended Storage Store at -20°C