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Invitrogen™ Ras (G12D Mutant) Recombinant Rabbit Monoclonal Antibody (HL10)
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Numéro de catalogue. PIMA536256
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Quantité:
100 μL
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Numéro de catalogue. Quantité
PIMA536256 100 μL
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Numéro de catalogue. PIMA536256 Fournisseur Invitrogen™ Code fournisseur MA536256

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Description

Rabbit Recombinant Monoclonal Antibody

Ras (G12D Mutant) Recombinant Monoclonal Antibody for IHC (P), Western Blot

Ras is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. The process of shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in Ras gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Spécifications

Antigène Ras (G12D Mutant)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone HL10
Concentration 1.5 mg/mL
Conjugué Unconjugated
Formule PBS with no preservative
Gène NRAS
Numéro d’acquisition du gène P01111, P08556
Alias du gène ALPS4; AV095280; CMNS; GTPase NRas; HRAS1; NCMS; neuroblastoma ras oncogene; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; NRAS; N-ras; N-ras protein part 4; NRAS1; NS6; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog
Symboles de gène NRAS
Espèces hôtes Rabbit
Immunogène Carrier-protein conjugated synthetic peptide surrounding mutant G12D of human K-Ras. The exact sequence is proprietary.
Méthode de purification Protein A
Quantité 100 μL
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 18176, 4893
Espèces cibles Human, Mouse
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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