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Invitrogen™ RAB3GAP1 Polyclonal Antibody
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Numéro de catalogue. PIPA5101803
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100 μL
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Numéro de catalogue. Quantity
PIPA5101803 100 μL
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Numéro de catalogue. PIPA5101803 Fournisseur Invitrogen™ Code fournisseur PA5101803
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RAB3GAP1.

RAB3GAP1, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Spécifications

Antigen RAB3GAP1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RAB3GAP1
Gene Accession No. Q15042, Q80UJ7
Gene Alias 1700003B17Rik; 4732493F09Rik; AL117896; KIAA0066; P130; Rab 3 GAP p130; Rab3 GAP p130; RAB3 GTPase activating protein catalytic subunit 1; RAB3 GTPase activating protein subunit 1; RAB3 GTPase activating protein subunit 1 (catalytic); RAB3 GTPase-activating protein 130 kDa subunit; Rab3 GTPase-activating protein catalytic subunit; RAB3GAP; Rab3-GAP; Rab3-GAP p130; Rab3gap1; RAB3GAP130; RGD1306487; WARBM1
Gene Symbols RAB3GAP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human RAB3GAP1(Accession Q15042), corresponding to amino acid residues S537-E587.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 226407, 22930
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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