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Tocris Bioscience™ Pyrimethamine

Catalog No. 391850
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50 mg
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Catalog No. Quantity
391850 50 mg
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Catalog No. 391850 Supplier Tocris Bioscience™ Supplier No. 3918/50

Description

Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor

Potent inhibitor of multidrug and toxin extrusion (MATE) transporters (Ki values are 46 and 77 nM for human MATE2-K-HEK293 and MATE1-HEK293 cells respectively). Also inhibits dihydrofolate reductase (DHFR) and STAT3. Decreases proliferation of human autosomal dominant polycystic kidney disease cells.

Chemical Identifiers

CAS 58-14-0
Molecular Formula C12H13ClN4

Specifications

Quantity 50 mg
Formula Weight 248.71
Purity >99%
Molecular Weight (g/mol) 248.71
Chemical Name or Material Pyrimethamine

Safety and Handling

Recommended Storage Store at Room Temperature