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Tocris Bioscience™ Probenecid

Catalog No. 410750
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50 mg
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Catalog No. Quantity
410750 50 mg
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Catalog No. 410750 Supplier Tocris Bioscience™ Supplier No. 4107/50
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Description

MRP inhibitor

Probenecid is an inhibitor of multidrug resistance-associated proteins (MRP). Probenicid inhibits OAT3, organic acid transport in the kidney and other organs and exhibits inhibitory activity against pannexin 1 channels (IC50 ∼ 150 μM). Probenecid potently inhibits SARS-CoV-2 replication in NHBE and Vero E6 cells (IC50 = 1.3 nM and 750 nM, respectively) and reduces lung virus titers in vivo. Probenicid also inhibits influenza A virus replication in vitro and in vivo.

Chemical Identifiers

CAS 57-66-9
Molecular Formula C13H19NO4S

Specifications

Quantity 50 mg
Formula Weight 285.36
Purity >98%
Molecular Weight (g/mol) 285.36
Chemical Name or Material Probenecid

Safety and Handling

Recommended Storage Store at Room Temperature