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Tocris Bioscience™ Chlorhydrate PJ 34
Description
Potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM). ∽1000-fold more potent than 3-Aminobenzamide (Cat. No. 0788). Protects primary neuronal cells from oxygen-glucose deprivation in vitro and reduces infarct size following focal cerebral ischemia in vivo. Displays protective effects against cisplatin -induced kidney injury. Also displays activity at Pim-1 and Pim-2 kinases at higher concentrations (IC50 values are 3.7 and 16 μM respectively).
Spécifications
Spécifications
| Nom ou substance chimique | PJ 34 hydrochloride |
| Quantité | 50 mg |
| Poids de formule | 331.8 |
| Pureté | >98% |
| Poids moléculaire (g/mol) | 331.8 |
Sécurité et manipulation
| Recommended Storage | Desiccate at Room Temperature |