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Tocris Bioscience™ PJ 34 hydrochloride

Catalog No. 325550
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10 mg
50 mg
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Catalog No. Quantity
325550 50 mg
325510 10 mg
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Catalog No. 325550 Supplier Tocris Bioscience™ Supplier No. 3255/50
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Description

Potent PARP inhibitor

Potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM). ∽1000-fold more potent than 3-Aminobenzamide (Cat. No. 0788). Protects primary neuronal cells from oxygen-glucose deprivation in vitro and reduces infarct size following focal cerebral ischemia in vivo. Displays protective effects against cisplatin -induced kidney injury. Also displays activity at Pim-1 and Pim-2 kinases at higher concentrations (IC50 values are 3.7 and 16 μM respectively).

Chemical Identifiers

CAS 344458-15-7
Molecular Formula C17H18ClN3O2

Specifications

Quantity 50 mg
Formula Weight 331.8
Purity >98%
Molecular Weight (g/mol) 331.8
Chemical Name or Material PJ 34 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature