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Tocris Bioscience™ Chlorhydrate PJ 34

Numéro de catalogue. 325550
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10 mg
50 mg
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Numéro de catalogue. Quantité
325550 50 mg
325510 10 mg
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Numéro de catalogue. 325550 Fournisseur Tocris Bioscience™ Code fournisseur 3255/50

Inhibiteur puissant de PARP

Potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM). ∽1000-fold more potent than 3-Aminobenzamide (Cat. No. 0788). Protects primary neuronal cells from oxygen-glucose deprivation in vitro and reduces infarct size following focal cerebral ischemia in vivo. Displays protective effects against cisplatin -induced kidney injury. Also displays activity at Pim-1 and Pim-2 kinases at higher concentrations (IC50 values are 3.7 and 16 μM respectively).

Identifiants chimiques

CAS 344458-15-7
Formule moléculaire C17H18ClN3O2

Spécifications

Nom ou substance chimique PJ 34 hydrochloride
Quantité 50 mg
Poids de formule 331.8
Pureté >98%
Poids moléculaire (g/mol) 331.8
Recommended Storage Desiccate at Room Temperature