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Thermo Scientific™ Sulfo-EMCS (N-ε-maleimidocaproyl-oxysulfosuccinimide ester)
Crosslink amines to sulfhydryls with this mid-length crosslinker composed of sulfo-NHS-ester and maleimide groups at ends of a water-soluble, 8-atom (9.4A) spacer arm.
Supplier: Thermo Scientific™ 22307
Description
Thermo Scientific™ Pierce Sulfo-EMCS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length spacer arm (9.4 Ås).
Highlights:
- Water-soluble
- Cleavable at pH 8.5 using hydroxylamine and heat
- Lactose dehydrogenase retained 60% of its activity after reversible crosslinking
- Reactive groups: sulfo-NHS esters (homobifunctional)
- Reactive toward: amino groups
Specifications
| Amine-Sulfhydryl | |
| Sulfo-EMCS | |
| No | |
| Upon receipt store desiccated at 4°C. | |
| Ambient | |
| Chemical Labeling | |
| Maleimide, Sulfo-NHS Ester | |
| Powder | |
| Water | |
| Yes |
| No | |
| 410.33 | |
| 9.4 AÌ | |
| No | |
| Pierce | |
| Heterobifunctional | |
| Short (<10 AÌ) | |
| 50 mg | |
| Standard | |
| Crosslinker |
For Research Use Only. Not for use in diagnostic procedures.