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Thermo Scientific™ EMCH (N-ε-maleimidocaproic acid hydrazide)

Catalog No. PI22106
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50 mg
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Catalog No. Quantity
PI22106 50 mg
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Catalog No. PI22106 Supplier Thermo Scientific™ Supplier No. LSG22106
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Description

Crosslink sulfhydryls to periodate-treated glycoprotein sugars with this mid-length (11.8A) crosslinker containing maleimide and hydrazide groups.

Thermo Scientific™ Pierce EMCH is a mid-length, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).

Highlights:

  • Sulfhydryl- and oxidized carbohydrate-reactive agent
  • Covalently couple the hydrazide group of EMCH to glycoproteins and other glycoconjugates after oxidation with sodium meta-periodate
  • Reactive groups: maleimide and hydrazide
  • Reactive toward: sulfhydryl and carbonyl (oxidized carbohydrate) groups
  • Use with EDC for reactivity toward carboxyl groups

Specifications

Chemical Reactivity Carbohydrate-Sulfhydryl
Cleavable No
Description EMCH
Molecular Weight (g/mol) 339.29
PEGylated No
Spacer Arm Length 11.8 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Amine, Hydrazide, Maleimide
Spacer Medium (10 to 30 Å)
Form Solid
Quantity 50 mg
Solubility Water
Format Standard
Water Soluble Yes
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.