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Thermo Scientific™ EGS (ethylene glycol bis(succinimidyl succinate))

Catalog No. PI21565
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Quantity:
1 g
Catalog No. Quantity
PI21565 1 g
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Catalog No. PI21565

Supplier: Thermo Scientific™ LSG21565

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Description

Crosslink amines to amines with this membrane permeable crosslinker composed of NHS-ester groups and a 16.1A hydroxylamine-cleavable spacer arm.

Thermo Scientific™ Pierce EGS is a crosslinker that contains amine-reactive NHS-ester ends around a 12-atom spacer arm, which can be cleaved by treatment with hydroxylamine at pH 8.5.

Highlights:

  • Cleavable at pH 8.5 using Hydroxylamine for 3-6 hours at 37°C
  • Lactose dehydrogenase retained 60% of its activity after reversible crosslinking with EGS
  • Reactive groups: NHS esters (homobifunctional)
  • Reactive toward: amino groups

Specifications

Chemical Reactivity Amine-Amine
Cleavable By Hydroxylamine
Description EGS
Molecular Weight (g/mol) 456.36
PEGylated No
Spacer Arm Length 16.1 Å
Content And Storage Upon receipt store at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety NHS Ester
Spacer Medium (10 to 30 Å)
Form Powder
Quantity 1 g
Solubility DMF, DMSO
Format Standard
Water Soluble No
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.