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Invitrogen™ Phospho-PP2A alpha (Tyr307) Polyclonal Antibody
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Numéro de catalogue. PIPA536874
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100 μL
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Numéro de catalogue. Quantity
PIPA536874 100 μL
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Numéro de catalogue. PIPA536874 Fournisseur Invitrogen™ Code fournisseur PA536874
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 38 kDa. Purity is >95% by SDS-PAGE.

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. The PP2A family comprises subfamily members PP2A alpha and PP2A beta. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.

Spécifications

Antigen Phospho-PP2A alpha (Tyr307)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene PPP2CA
Gene Accession No. P63330, P63331, P67775
Gene Alias B55-GAMMA; hypothetical protein; IMYPNO; IMYPNO1; Methyl-PPP2CA; MGC33570; PP2A; PP2A alpha; PP2A C terminal; PP2A L9; PP2A Leucine 9; Pp2a1; PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; Ppp2ca; PR52; PR55G; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; protein phosphatase 2 catalytic subunit alpha; protein phosphatase 2, catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, alpha isozyme; protein phosphatase 2,catalytic subunit alpha isozyme; protein phosphatase 2A alpha subunit; protein phosphatase 2A catalytic subunit alpha isoform; protein phosphatase 2a, catalytic subunit, alpha isoform; protein phosphatase type 2A catalytic subunit; protein phosphatase-2A; protein phosphatase-2A-alpha; R75353; replication protein C; RP-C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; unnamed protein product
Gene Symbols PPP2CA
Host Species Rabbit
Immunogen Synthetic phosphopeptide derived from human PP2A-alpha around the phosphorylation site of Tyrosine 307.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19052, 24672, 5515
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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