missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Phospho-AMPK alpha-2 (Thr172) Recombinant Rabbit Monoclonal Antibody (4F4)
Description
Phospho-AMPK alpha-2 (Thr172) Recombinant Monoclonal Antibody for Western Blot, ICC/IF, ELISA
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Spécifications
Spécifications
| Antigène | Phospho-AMPK alpha-2 (Thr172) |
| Applications | ELISA, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 4F4 |
| Concentration | 3 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gène | PRKAA2 |
| Numéro d’acquisition du gène | P54646, Q8BRK8 |
| Alias du gène | 2310008I11Rik; 5'-AMP-activated protein kinase catalytic subunit alpha-2; 5'-AMP-activated protein kinase, catalytic alpha-2 chain; A830082D05; ACACA kinase; Acetyl-CoA carboxylase kinase; AMP-activated protein kinase; AMP-activated protein kinase alpha-2 subunit variant 2; AMP-activated protein kinase alpha-2 subunit variant 3; AMP-activated protein kinase alpha-2 variant B; AMPK; AMPK alpha 2; AMPK alpha-2 chain; AMPK subunit alpha-2; AMPK2; AMPKa2; AMPKalpha2; AMPK-alpha-2 chain; EC 2.7.11.1; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; PRKAA; Prkaa2; protein kinase AMP-activated catalytic subunit alpha 2; protein kinase, AMP-activated, alpha 2 catalytic subunit |
| Afficher plus de résultats |