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Tocris Bioscience™ PF 04457845

Catalog No. 637425
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5 mg
25 mg
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Catalog No. Quantity
637425 25 mg
63745 5 mg
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Catalog No. 637425 Supplier Tocris Bioscience™ Supplier No. 6374/25

Description

Potent and selective irreversible FAAH inhibitor

PF 04457845 is a potent and selective irreversible FAAH inhibitor (IC50 = 7.2 nM, which is selective for FAAH over a panel of other serine hydrolases. PF 04457845 exhibits efficacy in a rat inflammatory pain model, and is orally bioavailable and brain penetrant.

Specifications

Chemical Name or Material N-3-Pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide
CAS 1020315-31-4
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C23H20F3N5O2
Formula Weight Observed MW: 455.43