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Tocris Bioscience™ PF 04418948

Catalog No. 481850
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10 mg
50 mg
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Catalog No. Quantity
481850 50 mg
481810 10 mg
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Catalog No. 481850 Supplier Tocris Bioscience™ Supplier No. 4818/50

Description

Potent and selective EP2 receptor antagonist

Potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a diverse panel of GPCRs and ion channels at a concentration of 10 μM. Inhibits PGE2-induced increases in intracellular cAMP; reverses PGE2-invoked relaxation of mouse trachea (IC50 = 2.7 nM).

Chemical Identifiers

CAS 1078166-57-0
Molecular Formula C23H20FNO5

Specifications

Quantity 50 mg
Formula Weight 409.41
Purity 98%
Molecular Weight (g/mol) 409.413
Chemical Name or Material PF 04418948

Safety and Handling

Recommended Storage Store at -20°C