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Invitrogen™ PBK Monoclonal Antibody (2C8)
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Numéro de catalogue. PIMA517144
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100 μL
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Numéro de catalogue. Quantity
PIMA517144 100 μL
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Numéro de catalogue. PIMA517144 Fournisseur Invitrogen™ Code fournisseur MA517144
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Description

Mouse Monoclonal Antibody

MA5-17144 targets PBK in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human samples. The MA5-17144 immunogen is purified recombinant fragment of human PBK expressed in E. Coli. MA5-17144 detects PBK which has a predicted molecular weight of approximately 36kDa.

PBK (TOPK) is a serine/threonine kinase that is related to the dual specific mitogen-activated protein kinase (MAPKK). The kinase is up-regulated in a variety of hematological malignancies, participates in activating lymphoid cells, and supports testicular function (spermatogenesis). Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

Spécifications

Antigen PBK
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2C8
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene PBK
Gene Accession No. Q96KB5
Gene Alias 2810434B10Rik; AW538537; Cancer/testis antigen 84; CT84; D14Ertd732e; epididymis luminal protein 164; HEL164; Lymphokine-activated killer T-cell-originated protein kinase; MAPKK-like protein kinase; Nori-3; PBK; PDZ binding kinase; PDZ-binding kinase; serine/threonine protein kinase; spermatogenesis-related protein kinase; SPK; T-LAK cell-originated protein kinase; TOPK
Gene Symbols PBK
Host Species Mouse
Immunogen Purified recombinant fragment of human PBK expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55872
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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