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Invitrogen™ Nrf2 Polyclonal Antibody
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Numéro de catalogue. PIPA527882
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Quantité:
100 μL
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Numéro de catalogue. Quantité
PIPA527882 100 μL
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Numéro de catalogue. PIPA527882 Fournisseur Invitrogen™ Code fournisseur PA527882

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: C8D30, 3xFlag-human NFE2L2-transfected 293T, MDA-MB-231 nuclear extract, MDA-MB-231 nuclear extract (30 μM tBHQ, 4hr), HepG2 (10 μM MG132 treatment for 15 hr). Predicted reactivity: Rhesus Monkey (99%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Nfr1 (also designated TCF11), Nrf2 and Nfr3 are bZIP transcription factors that heterodimer with Maf proteins to bind MARE (Maf recognition elements) sequences. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1.

Spécifications

Antigène Nrf2
Applications ChIP Assay, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugué Unconjugated
Formule PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gène NFE2L2
Numéro d’acquisition du gène O54968, Q16236, Q60795
Alias du gène AI194320; E4TF1-60; E4TF1A; HEBP1; Nfe2l2; NF-E2-related factor 2; NFE2-related factor 2; NF-E2-related factor-2; NFT2; NRF2; NRF2A; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2; Unknown (protein for IMAGE:7945830)
Symboles de gène NFE2L2
Espèces hôtes Rabbit
Immunogène Recombinant protein encompassing a sequence within the center region of human NRF2. The exact sequence is proprietary.
Méthode de purification Antigen affinity chromatography
Quantité 100 μL
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 18024, 4780, 83619
Espèces cibles Human, Mouse, Rat, Avian, Reptile, Zebrafish, Plant
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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