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Invitrogen™ NMDAR1 Polyclonal Antibody
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Numéro de catalogue. OPA104011
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Quantité:
25 μg
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Numéro de catalogue. Quantité
OPA104011 25 μg
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Numéro de catalogue. OPA104011 Fournisseur Invitrogen™ Code fournisseur OPA104011

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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with canine, chicken, human, non-human primate and Xenopus based on 100% sequence homology. In Western blot, this antibody detects an ~100 kDa protein representing the NR1 N1 splice variant from rat brain homogenate. It shows no cross-reactivity with the NR1 C1, C2, or C2 splice variants. Reconstitute with 50 μL of PBS. After reconstitution the antibody should be aliquotted and stored at -20ºC.

NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Spécifications

Antigène NMDAR1
Applications Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugué Unconjugated
Formule 5mM Ammonium bicarbonate with no preservative
Gène GRIN1
Numéro d’acquisition du gène P35438, P35439
Alias du gène GluN1; Glun1r; GluRdelta1; Glurz1; GluRzeta1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; glutamate ionotropic receptor NMDA type subunit 1; glutamate receptor; glutamate receptor ionotropic, NMDA 1; glutamate receptor subunit zeta 1; glutamate receptor, ionotropic, NMDA1 (zeta 1); glutamate receptor, ionotropic, N-methyl D-aspartate 1; GRIN1; M100174; MRD8; neurotransmitter receptor; NMDA R1 receptor C1 cassette; NMDA receptor 1; NMDA1; Nmdar; NMDAR1; NMD-R1; NMDZ1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMZ1; NR1; NR1C1; NR1C2; NR1C2'; NR1N1; pGluN1; Rgsc174; RP11-350O14.1
Symboles de gène GRIN1
Espèces hôtes Rabbit
Immunogène Synthetic peptide corresponding to amino acid residues specific to the NR1 subunit of rat GRIN1, N1 splice variant insert conjugated to KLH.
Méthode de purification Affinity Chromatography
Quantité 25 μg
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 14810, 24408
Espèces cibles Mouse, Rat
Contenu et stockage -20°C, Avoid Freeze/Thaw Cycles
Type de produit Antibody
Forme Lyophilized
Isotype IgG
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