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Nitrendipine

Catalog No. AAJ60841MC
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Quantity:
100 mg
500 mg
1 g
Catalog No. Quantity
AAJ60841MC 100 mg
AAJ60841ME 500 mg
AAJ6084103 1 g
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Catalog No. AAJ60841MC

Supplier: Thermo Scientific Chemicals J60841MC

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Description

L-type calcium channel blocker | CAS: 39562-70-4 | C18H20N2O6 | 360.366 g/mol

Nitrendipine modulates NMDA receptor channel function in mammalian neurons. Nitrendipine has been shown to inhibit neutrophil adhesion to vascular endothelium. It is used in the treatment of primary hypertension to decrease blood pressure. Nitrendipine is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Chemical Identifiers

CAS 39562-70-4
Molecular Formula C18H20N2O6
Molecular Weight (g/mol) 360.366
MDL Number MFCD00082255
InChI Key PVHUJELLJLJGLN-UHFFFAOYSA-N
Synonym nitrendipine, bayotensin, baypress, nidrel, nitrendipinum, nitrendipino, bylotensin, nitrendipin, deiten, nitrepin
PubChem CID 4507
ChEBI CHEBI:7582
IUPAC Name 5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C

Specifications

Color Yellow to Green
Quantity 100 mg
Merck Index 14,6576
Solubility Information Soluble in DMSO (17.5mg/ml),methanol (15mg/ml),ethyl acetate,and ethanol (25 mM). Insoluble in water.
Formula Weight 360.36
Physical Form Powder
Chemical Name or Material Nitrendipine

Safety and Handling

Hazard Category H302+H312+H332
Hazard Statement GHS H Statement
H302-H312-H332
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
Precautionary Statement P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P312-P330-P363-P501c
EINECSNumber 254-513-1
RTECSNumber US5653000
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only