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N-tert-Butyl-alpha-phenylnitrone, 97%

Catalog No. AAA1744206
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Catalog No. AAA1744206 Supplier Thermo Scientific Chemicals Supplier No. A1744206
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Description

CAS: 3376-24-7 | C11H15NO | 177.247 g/mol

N-tert-Butyl-a-phenylnitrone is a commonly-used free radical trap. It contains radical scavenging activity and an ability to inhibit Cox-2 (cyclooxygenase-2). N-tert-Butyl-a-phenylnitrone is an antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. N-tert-Butyl-a-phenylnitrone inhibits lipid peroxidation in rat liver microsomes. It also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-tert-Butyl-a-phenylnitrone is a commonly-used free radical trap. It contains radical scavenging activity and an ability to inhibit Cox-2 (cyclooxygenase-2). N-tert-Butyl-a-phenylnitrone is an antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. N-tert-Butyl-a-phenylnitrone inhibits lipid peroxidation in rat liver microsomes. It also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.

Solubility
Soluble in DMSO (10 mg/ml), chloroform (50 mg/ml), and water (20 mg/ml).

Notes
Store in a cool place. Reactive with oxidizing agents.

Chemical Identifiers

CAS 3376-24-7
Molecular Formula C11H15NO
Molecular Weight (g/mol) 177.247
MDL Number MFCD00008799
InChI Key IYSYLWYGCWTJSG-FMIVXFBMSA-N
Synonym e-n-benzylidene-2-methylpropan-2-amine oxide
PubChem CID 10313352
IUPAC Name N-tert-butyl-1-phenylmethanimine oxide
SMILES CC(C)(C)[N+](=CC1=CC=CC=C1)[O-]

Specifications

Melting Point 71°C to 75°C
Quantity 5 g
Beilstein 2044028
Merck Index 14,7056
Solubility Information Soluble in DMSO (10mg/ml),chloroform (50mg/ml),and water (20mg/ml).
Formula Weight 177.25
Percent Purity 98%
Chemical Name or Material N-tert-Butyl-alpha-phenylnitrone

Safety and Handling

EINECSNumber 222-168-6
TSCA Yes
Recommended Storage Keep cold

RUO – Research Use Only