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  7. N,O-Dimethylhydroxylamine hydrochloride, 98%

N,O-Dimethylhydroxylamine hydrochloride, 98%

Catalog No. p-7023671
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Catalog No. Quantity
AAA1746906 5 g
AAA1746914 25 g
AAA1746922 100 g
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Catalog No. AAA1746906

Supplier: Thermo Scientific Chemicals A1746906

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Description

CAS: 6638-79-5 | C2H8ClNO | 97.54 g/mol

N,O-Dimethylhydroxylamine hydrochloride is used as a reagent in the preparation of 2-acyloxazoles from 2-oxazolemagnesium chloride and N-methoxy-N-methyl-3-oxo-butyramide from diketene. It is also used in amide coupling reactions to form Weinreb amides, which are useful in the Weinreb ketone synthesis. In addition, it is used in the preparation of an inhibitor of the NLS-derived BC peptides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,O-Dimethylhydroxylamine hydrochloride is used as a reagent in the preparation of 2-acyloxazoles from 2-oxazolemagnesium chloride and N-methoxy-N-methyl-3-oxo-butyramide from diketene. It is also used in amide coupling reactions to form Weinreb amides, which are useful in the Weinreb ketone synthesis. In addition, it is used in the preparation of an inhibitor of the NLS-derived BC peptides.

Solubility
Soluble in water, dimethyl sulfoxide and methanol.

Notes
Hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents.

Chemical Identifiers

CAS 6638-79-5
Molecular Formula C2H8ClNO
Molecular Weight (g/mol) 97.54
MDL Number MFCD00012485
InChI Key USZLCYNVCCDPLQ-UHFFFAOYSA-N
Synonym n,o-dimethylhydroxylamine hydrochloride, n,o-dimethylhydroxylamine hcl, n-methoxymethylamine hydrochloride, methanamine, n-methoxy-, hydrochloride, o,n-dimethylhydroxylamine hydrochloride, n-methoxymethanamine hydrochloride, o,n-dimethyl-hydroxylamine hydrochloride, methoxy methyl amine hydrochloride, n,o-dimethylhydroxyamine hydrochloride, n,o-dimethylhydroxylaminehydrochloride
PubChem CID 81138
SMILES [H+].[Cl-].CNOC

Specifications

Melting Point 112°C to 115°C
Quantity 5 g
Beilstein 3650353
Sensitivity Hygroscopic
Solubility Information Soluble in water,dimethyl sulfoxide and methanol.
IUPAC Name hydrogen methoxy(methyl)amine chloride
Formula Weight 97.55
Percent Purity 98%
Chemical Name or Material N,O-Dimethylhydroxylamine hydrochloride

Safety and Handling

Hazard Category H315-H319
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
EINECSNumber 229-642-1
TSCA Yes
Recommended Storage Ambient temperatures; Store under Nitrogen

RUO – Research Use Only