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  6. N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%

N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%

Catalog No. AAH5902706
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Quantity:
5 g
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Catalog No. Quantity
AAH5902706 5 g
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Catalog No. AAH5902706 missing translation for 'mfr' Thermo Scientific Chemicals missing translation for 'supplierNo' H5902706

Description

CAS: 74844-91-0 | C11H19NO5 | 245.28 g/mol

It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

Solubility
Soluble in chloroform, dichloromethane and ethyl acetate.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Chemical Identifiers

CAS 74844-91-0
Molecular Formula C11H19NO5
Molecular Weight (g/mol) 245.28
MDL Number MFCD00076981
InChI Key MZMNEDXVUJLQAF-SFYZADRCSA-N
Synonym boc-hyp-ome, n-boc-trans-4-hydroxy-l-proline methyl ester, 2s,4r-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate, 1-tert-butyl 2-methyl 2s,4r-4-hydroxypyrrolidine-1,2-dicarboxylate, boc-l-hydroxyproline methyl ester, boc-hydroxyproline-ome, methyl trans-1-boc-4-hydroxy-l-prolinate, n-tert-butoxycarbonyl-trans-4-hydroxy-l-proline methyl ester, trans-1-tert-butoxycarbonyl-4-hydroxy-l-proline methyl ester, n-boc-trans-4-hydroxyl-l-proline methyl ester
PubChem CID 2734883
SMILES COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C

Specifications

Melting Point 92°C to 96°C
Quantity 5 g
Solubility Information Soluble in chloroform,dichloromethane and ethyl acetate.
Optical Rotation −65° (c=1 in Chloroform)
IUPAC Name 1-O-tert-butyl 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
Formula Weight 245.28
Percent Purity 97%
Chemical Name or Material N-Boc-trans-4-hydroxy-L-proline methyl ester

Safety and Handling

missing translation for 'healthHazard1' H315-H319-H335
missing translation for 'healthHazard3' P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only