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Tocris Bioscience™ MOMBA

Catalog No. 7926250
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250 mg
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7926250 250 mg
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Catalog No. 7926250 Supplier Tocris Bioscience™ Supplier No. 7926/250
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Description

Selective orthostatic agonist of hFFA2-DREADDs

MOMBA is a selective orthosteric agonist for human free fatty acid 2 (hFFA2) engineered receptors, designer receptors activated by designer drugs (DREADD), it shows no activity to wild-type hFFA2, hFFA3, and mouse FFA2. MOMBA inhibit forskolin-stimulated cAMP levels in cells expressing the hFFA2-DREADD receptor with improved potency and equivalent efficacy to Sorbic acid (Cat. No. 7119). In hFFA2-DREADD transgenic mice, MOMBA treatment significantly reduces gut transit and promotes concentration-dependent release of GLP-1 from colonic crypts. Orally bioavailable.

Specifications

Chemical Name or Material 4-Methoxy-3-methylbenzoic acid
CAS 6880-04-2
Quantity 250 mg
Target DREADD Activators
Molecular Formula C9H10O3
Purity 0.98