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Tocris Bioscience™ MI 2 (MALT1 inhibitor)

Catalog No. 484810
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50 mg
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484810 10 mg
484850 50 mg
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Catalog No. 484810 Supplier Tocris Bioscience™ Supplier No. 4848/10
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Description

MALT1 inhibitor

MALT1 inhibitor (IC50 = 5.84 μM). Binds directly to MALT1 and irreversibly suppresses protease function. Decreases NF-κB activity induced by MALT1. Inhibits cell proliferation and MALT1-mediated cleavage activity. Suppresses human TMD8 and HBL-1 activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) tumor xenografts in mice and primary human ABC-DLBCLs ex vivo.

Chemical Identifiers

CAS 1047953-91-2
Molecular Formula C19H17Cl3N4O3

Specifications

Quantity 10 mg
Formula Weight 455.72
Purity >98%
Molecular Weight (g/mol) 455.72
Chemical Name or Material MI 2 (MALT1 inhibitor)

Safety and Handling

Recommended Storage Store at +4°C