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  7. Thermo Scientific Chemicals Melatonine, 99%

Thermo Scientific Chemicals Melatonine, 99%

Catalog No. AC125360050
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5 g
Packaging:
Glass bottle
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AC125360050 5 g Glass bottle
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Catalog No. AC125360050 Supplier Thermo Scientific Chemicals Supplier No. 125360050
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Description

Melatonine, 99%, CAS # 73-31-4, is a hormone usually produced in the pineal gland and released into the blood.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Melatonine is a hormone produced by the pineal gland that shows several biological activities, including the somnolence, sleep-wake cycle, circadian rhythm, stress response, aging, and immunity activities

• It shows antioxidant, autocoid, paracoid, hormonal, anti- inflammatory and anti-apoptotic activities

Applications

• Melatonin shows neurohormonal activity and can upregulate antioxidant enzymes and inhibit rat NOS1

• Melatonin has been reported to be an activator of MEL-1A-R and MEL-1B-R

• The production and secretion of melatonine are dependent on beta-adrenergic receptor function

• During melatonine synthesis, the essential amino acid L-tryptophan is used as a precursor

• This compound inhibits apoptosis in immune cells and neurons, and enhances apoptotic cell death of cancer cells

• It can inhibit proliferation and metastasis of breast cancer cells by modulating Rho-associated kinase protein-1 expression

Chemical Identifiers

CAS 73-31-4
Molecular Formula C13H16N2O2
Molecular Weight (g/mol) 232.28
MDL Number MFCD00005655
InChI Key DRLFMBDRBRZALE-UHFFFAOYSA-N
Synonym melatonin, melatonine, n-acetyl-5-methoxytryptamine, circadin, 5-methoxy-n-acetyltryptamine, n-2-5-methoxy-1h-indol-3-yl ethyl acetamide, melatol, melatonex, melovine
PubChem CID 896
ChEBI CHEBI:16796
IUPAC Name N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
SMILES CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC

Specifications

Melting Point 116.0°C to 120.0°C
Color White or Cream to Yellow
Loss on Drying 0.5% max. (1 g, 105°C)
Infrared Spectrum Authentic
Assay Percent Range 98.5% min. (HPLC)
Packaging Glass bottle
Quantity 5 g
Beilstein 22, V,12, 42
Merck Index 15, 5884
Solubility Information Solubility in water: insoluble. Other solubilities: soluble in ethanol,benzene,toluene,hexane,acet,onitrile
Formula Weight 232.28
Percent Purity 99%
Physical Form Powder
Chemical Name or Material Melatonine
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Safety and Handling

EINECSNumber 200-797-7

RUO – Research Use Only