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Invitrogen™ Macro H2A.2 Monoclonal Antibody (OTI1F6)
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Numéro de catalogue. PIMA526598
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Quantité:
100 μL
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Numéro de catalogue. Quantité
PIMA526598 100 μL
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Numéro de catalogue. PIMA526598 Fournisseur Invitrogen™ Code fournisseur MA526598

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Description

Mouse Monoclonal Antibody

Macro H2A.2 Monoclonal Antibody for Western Blot, IHC (P)

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.

Spécifications

Antigène Macro H2A.2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1F6
Concentration 1 mg/mL
Conjugué Unconjugated
Formule PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gène H2AFY2
Numéro d’acquisition du gène Q9P0M6
Alias du gène Core histone macro-H2A.2; core histone macroH2A2.2; H2A histone family member Y2; H2A histone family, member Y2; H2AFY2; H2afy3; Histone macroH2A2; histone mH2A2; macroH2A2; mH2A2; RGD1561371
Symboles de gène H2AFY2
Espèces hôtes Mouse
Immunogène Human recombinant protein fragment corresponding to amino acids 2-261 of H2AFY2 produced in E.coli.
Méthode de purification Affinity Chromatography
Quantité 100 μL
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 55506
Espèces cibles Human
Contenu et stockage -20°C, Avoid Freeze/Thaw Cycles
Type de produit Antibody
Forme Liquid
Isotype IgG2a
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