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Thermo Scientific Chemicals Lovastatin, 98%

Lovastatin, CAS # 75330-75-5, is a cholesterol lowering compound and inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. | CAS: 75330-75-5 | C24H36O5 | 404.55 g/mol

$178.35 - $178.35

Chemical Identifiers

CAS 75330-75-5
Molecular Formula C24H36O5
Molecular Weight (g/mol) 404.55
MDL Number MFCD00072164
InChI Key PCZOHLXUXFIOCF-BXMDZJJMSA-N
Synonym lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin
PubChem CID 53232
ChEBI CHEBI:40303
IUPAC Name [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoateShow MoreShow Less
SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
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Catalog Number Mfr. No. Quantity Price Quantity  
AC458830050
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Thermo Scientific Chemicals
458830050
5 g
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Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Applications

• It blocks product ion of mevalonate, a critical compound in the production of cholesterol and isoprenoids

• It can increase cellular resistance to anticancer agents such as doxorubicin • It can induce apoptosis in myeloma cells

• It can cause cell cycle arrest in G1 and G2/M phase

• It also blocks PDGF receptor tyrosine phosphorylation and MAP kinase activation by PDGF

Specifications
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Safety and Handling

Safety and Handling

GHS H Statement
May cause an allergic skin reaction.
Suspected of causing cancer.
Suspected of damaging the unborn child.

GHS P Statement
Wear protective gloves/protective clothing.
IF ON SKIN: Wash with plenty of soap and water.
Obtain special instructions before use.
IF exposed or concerned: Get medical advice/attention.

GHS Signal Word: Warning

SDS
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RUO – Research Use Only