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Invitrogen™ KLF4 Polyclonal Antibody
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Numéro de catalogue. PIPA527441
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Quantité:
100 μL
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Numéro de catalogue. Quantité
PIPA527441 100 μL
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Numéro de catalogue. PIPA527441 Fournisseur Invitrogen™ Code fournisseur PA527441

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa. Predicted reactivity: Mouse (89%), Rat (89%), Cat (93%), Pig (93%), Sheep (92%), Rhesus Monkey (98%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Kruppel like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans. It is also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF) and belongs to a family of conserved Kruppel-like factor family of DNA binding zinc finger transcription factors. KLF4 exerts its functional relevance across varied cellular pathways. As one of the four Yamanaka factors, it plays a key role in reprogramming differentiated cells into pluripotent stem cells. Most studies have focused on its specific role in endothelial cell signaling, adipogenesis, differentiation, embryogenesis and cell cycle control. Localization plays an important role in the biological significance of this protein wherein nuclear localization is associated with its function as an oncogene and cytosolic localization with tumor suppression specific effect.

Spécifications

Antigène KLF4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugué Unconjugated
Formule PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gène KLF4
Numéro d’acquisition du gène O43474, Q60793
Alias du gène endothelial Kruppel-like zinc finger protein; epithelial zinc finger protein EZF; Ezf; Gklf; gut Kruppel-like factor; gut-enriched krueppel-like factor; high mobility group nucleosomal binding domain 3; high mobility group nucleosome-binding domain-containing protein 3; HMGN3; KLF4; Krueppel-like factor 4; Kruppel like factor 4; Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF); Kruppel-like factor 4 (gut); PNAS-24; PNAS-25; RP11-150J11.1; thyroid hormone receptor interacting protein 7; Thyroid receptor-interacting protein 7; TR-interacting protein 7; TRIP7; Zie
Symboles de gène KLF4
Espèces hôtes Rabbit
Immunogène Recombinant protein encompassing a sequence within the center region of human KLF4. The exact sequence is proprietary.
Méthode de purification Antigen affinity chromatography
Quantité 100 μL
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 16600, 9314
Espèces cibles Human, Mouse
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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