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Tocris Bioscience™ ISX 9
Description
ISX 9 is a neurogenic agent. Mediates neuroD reporter gene induction via activation of Ca2+ influx; increases expression of neurogenic differentiation 1 (NeuroD1) transcription factor. Induces neuronal differentiation in human cortical neuronal cells (HCN), adult mouse whole brain (MWB) and subventricular zone (SVZ) progenitors. Also shown to induce cardiomyogenic differentiation of Notch-activated epicardium-derived cells in vitro.
ISX 9 synthesized to Ancillary Material Grade also available.
For more information about how ISX 9 may be used, see our protocol: Transdifferentiating Fibroblasts into Neurons .
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 234.27 |
| Purity | >99% |
| Molecular Weight (g/mol) | 234.273 |
| Chemical Name or Material | ISX 9 |
Safety and Handling
| Recommended Storage | Store at +4°C |