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Tocris Bioscience™ ISX 9

Catalog No. 443910
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10 mg
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Catalog No. Quantity
443910 10 mg
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Catalog No. 443910 Supplier Tocris Bioscience™ Supplier No. 4439/10
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Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation

ISX 9 is a neurogenic agent. Mediates neuroD reporter gene induction via activation of Ca2+ influx; increases expression of neurogenic differentiation 1 (NeuroD1) transcription factor. Induces neuronal differentiation in human cortical neuronal cells (HCN), adult mouse whole brain (MWB) and subventricular zone (SVZ) progenitors. Also shown to induce cardiomyogenic differentiation of Notch-activated epicardium-derived cells in vitro.

ISX 9 synthesized to Ancillary Material Grade also available.

For more information about how ISX 9 may be used, see our protocol: Transdifferentiating Fibroblasts into Neurons .

Chemical Identifiers

CAS 832115-62-5
Molecular Formula C11H10N2O2S

Specifications

Quantity 10 mg
Formula Weight 234.27
Purity >99%
Molecular Weight (g/mol) 234.273
Chemical Name or Material ISX 9
Recommended Storage Store at +4°C