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  6. Thermo Scientific Chemicals Ionomycin, 96%

Thermo Scientific Chemicals Ionomycin, 96%

Numéro de catalogue. AAJ62448MCR
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AAJ62448LB0 5 mg
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Numéro de catalogue. AAJ62448MCR Fournisseur Thermo Scientific Chemicals Code fournisseur J62448MCR
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Description

Highly selective and potent calcium ionophore | CAS: 56092-81-0 | C41H72O9, C41H72O9 | 709.02 g/mol

Ionomycin free acid is a beneficial tool in research to raise intracellular calcium levels. Also this antibiotic can be used to study the calcium transport across the plasma membrane. It has been shown to induce central demyelination , inhibit adrenal bovine TREK-1 channels , and to regulate cell division of mature human B cells . It is used to study the effects of calcium flux on endoplasmic reticulum (ER) stress, mitochondrial stress and intrinsic apoptosis mechanisms. It is also used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2, and IL-4 usually in conjunction with PMA.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Identifiants chimiques

CAS 56092-81-0
Molecular Formula C41H72O9

Spécifications

Quantity 1 mg
Description Colorless
Content And Storage -30°C to -10°C
For Use With (Application) Highly selective and potent calcium ionophore
Formula Weight 709.02
Odor Alcohol-like
Product Type Ionomycin
Form Solution in ethanol
Beilstein 3642126
InChI Key PGHMRUGBZOYCAA-OJFQOPKISA-N
SMILES C[C@H](CCC(O)=O)C[C@H](C)C[C@H](C)C(=O)\C=C(/O)[C@H](C)C[C@H](C)C\C=C\[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)CC1CC[C@](C)(O1)C1CC[C@](C)(O1)[C@@H](C)O
IUPAC Name (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-22-[(2S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl-[2,2'-bioxolan]-5-yl]-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoic acid
Molecular Weight (g/mol) 709.02
Assay 98%
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Sécurité et manipulation

Recommended Storage Store at -20°C

RUO – Research Use Only