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Invitrogen™ Image-iT™ TMRM Reagent (mitochondrial membrane potential indicator)

Catalog No. I34361
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I34361 5 x 100 μL
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Catalog No. I34361 Supplier Invitrogen™ Supplier No. I34361
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Description

Healthy mitochondrial membranes maintain a difference in electrical potential between the interior and exterior of the organelle, referred to as a membrane potential.

Tetramethylrhodamine, methyl ester (TMRM) is a cell-permeant dye that accumulates in active mitochondria with intact membrane potentials. If the cells are healthy and have functioning mitochondria, the signal will be bright. Upon loss of the mitochondrial membrane potential, TMRM accumulation will cease and the signal will dim or disappear. TMRM signal can be detected with fluorescence microscopy, flow cytometry, cell sorting, high-throughput screening, and high content analysis.

• For live-cell dynamic study of mitochondrial membrane potential (not fixable)
• Detectable with RFP/TRITC filter set (absorbance peak: 548 nm, emission peak: 574 nm)
• multiplexable with green, deep red, violet, and blue emission dyes, such as GFP, DAPI, Hoechst, HCS LipidTOX, and LysoTracker Deep Red

Specifications

Color Orange
Content And Storage Store in freezer -5°C to -30°C and protect from light.
Product Type Reagent
Product Line Molecular Probes
Quantity 5 x 100 μL
Shipping Condition Wet Ice

For Research Use Only. Not for use in diagnostic procedures.