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  6. Invitrogen™ IL-2 Monoclonal Antibody (JES6-5H4), PerCP-Cyanine5.5, eBioscience™, Invitrogen™

Invitrogen™ IL-2 Monoclonal Antibody (JES6-5H4), PerCP-Cyanine5.5, eBioscience™, Invitrogen™

Numéro de catalogue. 5015869
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25 μg
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Numéro de catalogue. Quantité
5015869 25 μg
5015870 100 μg
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Numéro de catalogue. 5015869 Fournisseur Invitrogen™ Code fournisseur 45702180

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Description

Rat Monoclonal Antibody

Description: The JES6-5H4 antibody reacts with mouse interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine. Applications Reported: This JES6-5H4 antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This JES6-5H4 antibody has been tested by intracellular staining and flow cytometric analysis of stimulated mouse splenocytes. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

Spécifications

Antigène IL-2
Applications Flow Cytometry
Classification Monoclonal
Clone JES6-5H4
Concentration 0.2 mg/mL
Conjugué PerCP-Cyanine5.5
Formule PBS with 0.09% sodium azide; pH 7.2
Gène IL2
Numéro d’acquisition du gène P04351
Alias du gène aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Symboles de gène IL2
Espèces hôtes Rat
Méthode de purification Affinity chromatography
Quantité 25 μg
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 16183
Espèces cibles Mouse
Contenu et stockage 4°C, store in dark, DO NOT FREEZE!
Type de produit Antibody
Forme Liquid
Isotype IgG2b κ
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For Research Use Only.