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Invitrogen™ IFNAR1 Monoclonal Antibody (85228), PE
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Numéro de catalogue. PIMA523630
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100 Tests
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Numéro de catalogue. Quantité
PIMA523630 100 Tests
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Numéro de catalogue. PIMA523630 Fournisseur Invitrogen™ Code fournisseur MA523630

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Description

Mouse Monoclonal Antibody

In direct ELISAs, does not cross-react with recombinant human (rh) IFN- gamma R1, rhIFN-gamma R2, recombinant mouse IFN-alpha / beta R2, rhIL-10 R beta, rhIL-10 R alpha, or rhIL-20 R beta.

Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).

Spécifications

Antigène IFNAR1
Applications Flow Cytometry
Classification Monoclonal
Clone 85228
Conjugué PE
Formule Buffered saline solution with ≤0.5% BSA and 0.09% sodium azide
Gène Ifnar1
Numéro d’acquisition du gène P17181
Alias du gène alpha-type antiviral protein; AVP; beta-type antiviral protein; CD118; CRF2-1; cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; H3K1; Ifar; IFN R1; IFNalpha/beta R1; IFN-alpha/beta receptor 1; IFN-alpha/betaR; IFNalpha/betaR1; IFN-alpha/betaR1; IFN-alpha/betaRalpha; IFNalpha/beta-Ralpha; IFN-alpha-REC; IFNAR; Ifnar1; IFNBR; IFNR1; IFN-R-1; Ifrc; INF-a receptor; Infar; interferon (alpha and beta) receptor 1; interferon (alpha, beta and omega) receptor 1; interferon alpha and beta receptor subunit 1; interferon alpha/beta receptor 1; interferon receptor 1; interferon-alpha/beta receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1
Symboles de gène Ifnar1
Espèces hôtes Mouse
Immunogène Sf 21-derived recombinant human IFN-alpha/beta R1 Lys28-Lys436.
Méthode de purification Protein A/G
Quantité 100 Tests
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 3454
Espèces cibles Human
Contenu et stockage 4°C, store in dark, DO NOT FREEZE!
Type de produit Antibody
Forme Liquid
Isotype IgG1
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